Notes
Outline
Cervical Cancer
Screening· Evaluation· Treatment
About this Presentation
This presentation is intended to help women take an active role in their health care.  It does not replace the judgment of a health care professional in diagnosing and treating disease.
GCF Mission Statement
The mission of the Gynecologic Cancer Foundation (GCF) is to ensure public awareness of gynecologic cancer prevention, early diagnosis and proper treatment.  In addition the Foundation supports research and training related to gynecologic cancers.  GCF advances this mission by increasing public and private funds that aid in the development and implementation of programs to meet these goals.
GCF gratefully acknowledges the National Cervical Cancer Coalition (NCCC) for their support of this educational presentation.  For more information on NCCC, call (800) 685-5531 or visit the Web site at www.nccc-online.org.
Information Hotline: (800) 444-4441
A list of specially trained gynecologic oncologists practicing in your local area can be received by phone, fax or mail
A directory of all GCF members practicing in the U.S. can also be mailed upon request
Free educational brochures on gynecologic health
Women’s Cancer Network: www.wcn.org
Confidential gynecologic (ovarian, endometrial, cervical) and breast cancer risk assessment
Comprehensive women’s cancer information including gynecologic, breast, lung and colon cancers
Links to other sources of cancer information
"Cervical Cancer Screening and Prevention"
Cervical Cancer Screening and Prevention
New cancer diagnoses in the U.S.
2003 Statistics:
Breast 211,300
Uterus (womb)   40,100
Ovary   25,400
Cervix   12,200
Vulva     4,000
Source: American Cancer Society.
What is cervical cancer?
It is a cancer of the female reproductive tract
It is the most common cause of cancer death in the world where Pap tests are not available
It is the easiest gynecologic cancer to prevent through screening
What is the female reproductive tract?
Vulva
Vagina
Cervix
Uterus
Fallopian tubes
Ovaries
What is the cervix?
Opening of the uterus (womb) into the vagina
Two cell types present (squamous and glandular)
Cervical cancers tend to occur where the two cell types meet
How common is cervical cancer?
500,000 women worldwide die of cervical cancer annually
50-60 million women in the U.S. have a Pap test each year
3-5 million women in the U.S. have an abnormal result
12,200 new cervical cancers diagnosed in the U.S. per year
4,100 deaths from cervical cancer in the U.S. per year
What causes cervical cancer?
The central cause of cervical cancer is human papillomavirus or HPV:
HPV is sexually transmitted
The HPV detected today could have been acquired years ago
There are many different types of HPV
Low-risk types can cause warts
High-risk types can cause precancer and
cancer of the cervix
If I have HPV, does it mean I will get cancer?
NO!
In most cases HPV goes away
Only women with persistent HPV (where the virus does not go away) are at risk for cervical cancer
How common is HPV?
Most men and women who have had sex have been exposed to HPV
More than 75% of sexually active women tested have been exposed to HPV by
age 18-22
Who is at risk?
Women who have ever had sex
Women who have had more than one partner
Women whose partner (s) has had more than one sexual partner
Women with other sexually transmitted diseases
Who is at risk?
Women who do not have Pap tests
Women with immune problems
Steroid medications
Transplanted organs
Chemotherapy
HIV
Women who smoke
How do I lower my risk?
Delay onset of sexual activity
Know your sexual partner
Do not smoke
Maintain a healthy diet and lifestyle
Practice safe sex
What is a Pap test?
A test which collects cells from the surface of the cervix and looks for any abnormal cells
Abnormal cells can be treated before cervical cancer develops
When cancer is detected early, it is easier
to treat
What a Pap test is NOT!
A pelvic exam
A test for ovarian or uterine cancer
A biopsy
When do I need my first Pap test?
Three years after the onset of sexual intercourse
No later than age 21
How often do I need a Pap test?
Every year until age 30
After age 30, if you have only had normal results, you may have them every two to three years after discussion with your physician and evaluation of your risk factors
I feel fine, so why do I need a Pap test?
A Pap test can  find treatable changes of the cervix (precancer) before you have a symptom or notice a problem
Once a problem is symptomatic, it is harder
 to treat
Why do I need to keep getting tested?
The test is not perfect
Changes (abnormalities) may occur since the last test
It may take many years for changes to develop or be detected
Your risk changes if you have new partners
What is the best time to have a Pap test?
Schedule your Pap when you are not having a menstrual period
It is best to abstain from intercourse and avoid use of tampons or douches for two days before your Pap test
What should I expect when I have
a Pap test?
Feet are placed in stirrups (foot holders)
A speculum (thin duck-billed instrument) is inserted into vagina to see the cervix
You may have brief discomfort which is usually mild
You may have some spotting afterward
How do I find out about my Pap test results?
You may ask to have a copy mailed to you
You may call for your results
If you have an abnormal result, it is extremely  important to follow-up for the recommended testing
Even after a normal Pap test, it is still important to report any symptoms of abnormal vaginal bleeding, discharge or pain to your doctor and call to be seen right away
Do I need a Pap test if I had a hysterectomy?
If you had treatment for precancer or cancer of the cervix, you may need a Pap test
If the cervix was left in place at the time of your hysterectomy, you will still need Pap tests
Preventive health care is still important even if you do not need a Pap test
Is there an age when I can stop having Pap tests?
    The American Cancer Society recommends that screening stop at age 70, if three or more recent tests are normal, and there have been no abnormal results in the last 10 years.
What is new in screening and prevention?
Liquid cytology-thin layer cytology
Combination of HPV test and Pap is now available for women 30 years of age and older
Pap test computer reviews
Vaccines for HPV currently being tested
"Evaluation of the Abnormal Pap..."
Evaluation of the Abnormal Pap Test
and Treatment of Precancer
Abnormal Pap test – How common is it?
What is an HPV test?
A test sometimes used to determine if you need further evaluation
Cells are collected just like a Pap test
It checks for high-risk HPV
What happens if I have an abnormal
Pap test?
 ASC-US management options:
HPV testing
Repeat Pap
Colposcopy
ASC-H, LSIL, HSIL, AGC, AIS, cancer
Colposcopy
Possibly endometrial biopsy for AGC
AIS / cancer: referral to gynecologic oncologist
What is a colposcopy?
Colposcopy:
Use of a magnifying instrument
Application of a vinegar-like solution onto the cervix
See abnormalities that can’t be seen with the naked eye
Feels like getting a Pap test, but lasts  longer
What is a cervical biopsy?
Biopsy:
Removal of a small piece of tissue from the cervix
May feel like getting a Pap test or like a menstrual cramp that lasts a few seconds
What does the biopsy result mean?
Mildly abnormal (CIN I)
observation preferred
More abnormal (CIN II)
treatment
Precancer (CIN III)
treatment
Cancer
Gynecologic oncology consultation
What are the treatment options for CIN?
LEEP
Laser
Cryotherapy
Cone Biopsy
In special circumstances a hysterectomy may be recommended
What can I expect after treatment for CIN?
Estimates of cure range from 73-90% with a single treatment
The risk for invasive cancer following treatment is about 1%
Therefore, you still need to have regular Pap tests
Minimal, if any, impact on fertility
What you can do?
Take Control - Protect Yourself
1) Ask your doctor about an appropriate Pap test screening interval for you
2) Make sure that you get a Pap test at the recommended time
3) Find out how and when you will learn about the results of your Pap test
4) Follow-up! Don’t assume that no news is
good news
5) Do not smoke
"Cervical Cancer"
Cervical Cancer
What are the symptoms of cervical cancer?
Abnormal bleeding
Between periods
With intercourse
After menopause
Unusual vaginal discharge
Other symptoms
Leg pain
Pelvic pain
Bleeding from the rectum or bladder
Some women have no symptoms
What should I do if I have just been diagnosed with cervical cancer?
Find a gynecologic oncologist
Call 1-800-444-4441
Discuss treatment options
Conization
Hysterectomy
Radical hysterectomy
Radiation with chemotherapy
Ask about clinical trials (Gynecologic Oncology Group)
Other considerations
Preserve your fertility
Preserve your ovaries
Clinical staging of cervical cancer
What is a cervical conization?
Conization:
Removes a cone-shaped piece of tissue
Often allows for diagnosis and treatment
Performed with local anesthesia in the office or under general anesthesia in the operating room
What is a radical hysterectomy?
Treatment option for early stage cancer
Not the same as the usual hysterectomy
Surgical removal of the uterus, cervix and upper vagina with the surrounding tissues
Lymph nodes are removed
Removal of the ovaries is not required
What is radiation with
chemotherapy (chemoradiation)?
Standard of care for advanced cancer
Treatment requires:
External radiation
Internal radiation
Low dose chemotherapy given at the same time
Cervical cancer: What is the chance of survival after treatment?
Re-establishing Wellness
Restoring wellness is a gradual process
Some women find strength from:
Friends and family
Support groups
Spiritual work
Counseling
Exercise
The challenges and the journey are different for each woman with cervical cancer
How do I get my friends to have a Pap test?
Tell her it doesn’t hurt
Offer her a ride
Offer help with child care
Help her get an appointment
Help her find the right health care provider
Empower her with information: Tell your friend about the importance of health prevention
Cervical Cancer Presentation Participants

GCF gratefully acknowledges the following individuals who contributed to this educational presentation:
Bobbie Gostout, M.D., Editor
Wendy Brewster, M.D.
Karen Carlson
Thomas Cox, M.D.
Juan Felix, M.D.
Hollis Forster
Christine Holschneider, M.D.
Beth Karlan, M.D.
Alan Kaye
Hershel Lawson, M.D.
Suzy Lockwood, R.N., M.S.N., Ph.D.
Saralyn Mark, M.D.
F.J. Montz, M.D., K.M. (1955-2002)
Mitchell Morris, M.D.
Karl Podratz, M.D., Ph.D.
Karen Riordan
Debbie Saslow, Ph.D.
Evelyn Schulman
Alice Spinelli, M.S.N., A.R.N.P.
Joan Walker, M.D.
Leslie Walton, M.D.
Thomas Wright, Jr., M.D.
GCF Supporting Organization
    This educational effort was undertaken by the Gynecologic Cancer Foundation with support from the National Cervical Cancer Coalition (NCCC).  GCF gratefully acknowledges and thanks NCCC for its efforts related to cervical cancer public outreach.
For more information:
National Cervical Cancer Coalition
16501 Sherman Way
Suite #110
Van Nuys, CA 91406
Toll Free Hotline (800) 685-5531
Phone:  (818) 909-3849
Fax:  (818) 780-8199
Email:  info@nccc-online.org
Web site:  www.nccc-online.org
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