Treatment for Nonmetastatic Gestational Trophoblastic Disease
Treatment for nonmetastatic GTD is almost always chemotherapy. With this type of there is no concern for disease outside the uterus. There is, though, an issue with the hCG. It may have stayed steady for weeks after the molar pregnancy was removed. Or it may have gone up over a few weeks after the removal.
The chemotherapy is usually a single agent treatment. It uses either methotrexate or actinomycin D. If you no longer want to have children, hysterectomy may be considered. A hysterectomy will lower the total number of cycles of chemotherapy you will need.
With proper treatment, the cure rate for this disease is close to 100 percent. A recent study suggests that actinomycin-D may be better than methotrexate. The reasons include quicker response to chemotherapy and a lower failure rate.