Common Tumor Suppressor Genes
| Known Tumor Suppressor Target | Cancer(s) It Is Linked To |
|---|---|
| Rb | Retinoblastoma, sarcoma |
| WT1 | Wilms’ tumor |
| P53 | Lung, colorectal, renal, ovarian, brain, and breast cancers |
| APC | Colorectal cancer |
| MSH2, MLH1 | Colon and endometrial cancer |
| BRCA1 | Breast and/or ovarian cancer |
| BRCA2 | Breast and/or ovarian cancer |
| DPC4 | Pancreatic cancer |
| NF2 | Acoustic neuroma, meningioma |